Neuromodulation as a Drug-Free "Digital Therapeutic"
In 2026, the definition of "migraine drugs" has expanded to include Neuromodulation Devices that are often prescribed alongside or instead of traditional pharmaceuticals. These devices use mild electrical or magnetic pulses to calm the overactive nerves involved in migraine.
Supraorbital Stimulators: Worn like a headband, these stimulate the trigeminal nerve.
Vagus Nerve Stimulators: Handheld devices applied to the neck to inhibit pain signals.
Remote Electrical Neuromodulation (REN): A wearable arm patch that uses the body’s natural "conditioned pain modulation" to shut down a migraine attack via a mobile app.
These devices are particularly useful for pregnant patients or those who experience severe side effects from oral medications.
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